Comparison of PD-L1, EGFR, ALK, and ROS1 Status Between Surgical Samples and Cytological Samples in Non-Small Cell Lung Carcinoma
Articles > Article · 2021
Authors: Zubeyde Ekin, Deniz NART, Pinar SAVAŞ, Ali VERAL
BALKAN MEDICAL JOURNAL, Journal Indexed in SCI Expanded, International, 2021, vol 38, pp 287-295
DOI: 10.5152/balkanmedj.2021.20086
Summary
Background: The expression levels of Programmed death ligand-1 (PD-L1), epidermal growth factor receptor (EGFR), anaplastic lymphoma tyrosine kinase gene (ALK), and proto-oncogene tyrosine-protein kinase 1 ROS (ROS1) are important for targeted treatment selection in advanced lung cancer. Most patients with lung cancer are diagnosed at an advanced stage and have no chance of surgery. For this reason, the accuracy and reliability of cytology samples for detecting those markers is important in patients whose histological sampling cannot be performed.