Comparison of PD-L1, EGFR, ALK, and ROS1 Status Between Surgical Samples and Cytological Samples in Non-Small Cell Lung Carcinoma
Makaleler > Tam Makale · 2021
Yazarlar: Zubeyde Ekin, Deniz NART, Pinar SAVAŞ, Ali VERAL
BALKAN MEDICAL JOURNAL, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2021, cilt 38, ss 287-295
DOI: 10.5152/balkanmedj.2021.20086
Özet
Background: The expression levels of Programmed death ligand-1 (PD-L1), epidermal growth factor receptor (EGFR), anaplastic lymphoma tyrosine kinase gene (ALK), and proto-oncogene tyrosine-protein kinase 1 ROS (ROS1) are important for targeted treatment selection in advanced lung cancer. Most patients with lung cancer are diagnosed at an advanced stage and have no chance of surgery. For this reason, the accuracy and reliability of cytology samples for detecting those markers is important in patients whose histological sampling cannot be performed.