Lens superoxide dismutase and catalase activities in diabetic cataract
Makaleler > Tam Makale · 2002
Yazarlar: BİLGİN OZMEN, DİLEK OZMEN, E Erkin, INCI GUNER, Sara HABİF, OYA BAYINDIR
Clinical Biochemistry, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2002, cilt 35, ss 69-72
DOI: 10.1016/s0009-9120(01)00284-3
Özet
Objective: Biochemical evidence suggests that the oxidative damage of the tens proteins is involved in the genesis of senile cataract and the development of diabetes-related pathologic changes such as the formation of cataracts. In particular, lens proteins are subject to extensive oxidative modification. Oxidative damage either decreases the antioxidant capacity or decreased antioxidant capacity results in oxidative damage. The purpose of this study was to analyze the activities of the antioxidant enzymes such as Cu,Zn Superoxide Dismutase (Cu,Zn-SOD) and catalase in the cataractous tenses of the type 2 diabetic group and cataractous lenses of the senile group.