Apoptosis in the development and pathophysiology of the limbic system
Articles > Article · 2012
Authors: Yiğit UYANIKGİL, N. Ceren Sümer, Ḧseyin Avni Balcioǧlu
JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, Journal Indexed in SCI Expanded, International, 2012, vol 29, pp 431-436
Summary
Limbic system is involved in the intangible functions of brain like emotions, inborn and acquired emotional responses, self-awareness, ability to understand intentions of others and and memory. Apoptosis has a critical role in the developing brain and disruption of developmental apoptosis may lead to neurodevelopmental disorders. This review summarizes apoptotic processes in the limbic system during fetal brain development in normal and pathological conditions and focuses on the molecular mechanisms of apoptosis.