Mortality in Psoriatic Arthritis patients, changes over time and the impact of COVID-19: Results from a multicenter Psoriatic Arthritis Registry (PsART-ID)
Diğer yayınlar > Diğer · 2022
Yazarlar: Abdulsamet Erden, Gizem Ayan, Levent Kilic, Dilek Solmaz, Sibel Bakirci, Gezmis Kimyon, Esen Kasapoglu Günal, Atalay Dogru, Özün Bayindir, Ediz Dalkilic, Cem Özisler, Servet Akar, Gözde Yildirim Cetin, Emine Figen Tarhan, Orhan Küçüksahin, Ahmet Omma, Emel Gonullu, Fatih Yildiz, Emine Duygu Ersozlu, Muhammed Cinar, Abdurrahman Tufan, Seval Pehlevan, Serpil Ergulu Esmen, Sema Yilmaz, Tuncay Duruoz, Timucin Kasifoglu, Veli Yazısız, Kenan AKSU, Sibel Zehra Aydin, Umut Kalyoncu
Diğer, Uluslararası, 2022,
Özet
Abstract BackgroundThis study aimed to assess the mortality of PsA before and during the COVID-19 pandemic.MethodsFrom the prospective, multicenter PsART-ID (Psoriatic Arthritis Registry-International Database), patients from Turkey were analyzed by linking the registry to the Turkish Cause of Death Registry. The outcome of interest was death from any cause, pre-pandemic (since the onset of registry – March 2014- March 2020), and during the pandemic (March 2020-May 2021). The crude mortality rate and standardized mortality ratio (SMR) were determined. ResultsThere were 1216 PsA patients with a follow-up of 7500 patient-years. Overall, 46 deaths (26 males) were observed. In the pre-pandemic period, SMR for PsA vs the general population was 0.95 (0.61-1.49), being higher in males [1.56 (0.92-2.63)] than females [0.62 (0.33-1.17)]. The crude mortality rate in PsA doubled during the pandemic (pre-pandemic crude mortality rate: 5.07 vs 10.76 during the pandemic) with a higher increase in females (2.9 vs 8.72) than males (9.07 vs 14.73).Conclusion The mortality in PsA was found similar to the general population in the pre-pandemic era. The mortality rates in PsA doubled during the pandemic. Whether PsA patients have more risk of mortality than the general population due to COVID-19, needs further studies.