Pulmonary Function in The Patients With Thalassemia
Makaleler > Tam Makale · 1995
Yazarlar: Esen Demir, Canan Vergin, Nazan Çetingül, Kaan Kavaklı, Senay Öztop, Güngör Nişli, Remziye Tanaç, Ertürk Erdinç, Müzeyyen Varol
The Journal of Tepecik Education and Research Hospital, Uluslararası, 1995, cilt 5, ss 52-56
Özet
Abnormalities of pulmonary function have been deseribed in hypertransfused patients with thalassemia.We evaluated pulmonary function tests of 15 homozygous beta thalassemia patients, 9 boys, 6 girls, between the ages of 7-25 years, who were transfused and chetated regularly.None of the patients had acute pulmonary disease or familial lung problems.The values of vital capacity, forced vital capacity, forced expiratory volume in 1 minute, forced expiratory volume in 1 minute/vital capacity, forced expiratory volume in 1 minute/ forced vital capacity, peak expiratory flow rate, maximum volume at 25-50-75 % vital capacity were evaluated in these patients, and in 10 patients, single-breath carbon monoxide diffusion was measured.In 10 patients pulmonary function tests were normal, there were obstructive lung disease in 3 patients, restrictive and combined lung disease in 1 patient, and carbon monoxide diffusion was normal in 3 of the 10 patients.These results indicate that abnormalities of pulmonary function tests are common in thalassemia and that patient age, transfusion history and iron accumulation are not important factors in the genesis of these pulmonary abnormalities.