Alpha 2 integrin gene (ITGA2) polymorphism in renal transplant recipients with and without drug induced gingival overgrowth
Articles > Article · 2013
Authors: Ali GÜRKAN, Gülnur EMİNGİL, Beral AFACAN, Afig BERDELİ, FATMA GÜL ATİLLA
Archives of Oral Biology, Journal Indexed in SCI Expanded, International, WoS, 2013, vol 59, pp 283-288
DOI: 10.1016/j.archoralbio.2013.12.003
Summary
Background: Variances in fibroblasts' alpha 2 beta 1 integrin intensity may lead to altered adhesion to type I collagen and consequently to suppression of phagocytosis which may be one of the mechanisms for drug induced gingival overgrowth. The present study aimed to evaluate the genotype and allele frequencies of alpha 2 integrin +807 gene in renal transplant patients with and without gingival overgrowth.