Decreased ratio of CD4/CD8 lymphocytes might be predictive for successful interferon alpha and lamivudine combined therapy in childhood chronic hepatitis B infection: A preliminary study
Articles > Article · 2003
Authors: F GENEL, F UNAL, F OZGENC, Güzide AKSU, S AYDOGDU, Necil KÜTÜKÇÜLER, RV YAĞCI
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, Journal Indexed in SCI Expanded, International, 2003, vol 18, pp 645-650
DOI: 10.1046/j.1440-1746.2003.03050.x
Summary
Background: In the development of chronic hepatitis with hepatitis B virus infection and in response to therapy, the immune status of the infected host plays a critical role. In this study, immunological variables were assessed in patients before interferon alpha and lamivudine therapy to determine if any pretreatment immunological parameter could be an indicator of response to therapy in childhood chronic hepatitis B infection.