PTCalc: open computational tools for pharmaceutical technology
Diğer yayınlar > Diğer · 2026
Yazarlar: Mehmet Ali EGE
Diğer, Uluslararası, 2026,
Özet
Open-source web application (Blazor Server, .NET 10) and library for pharmaceutical technology computations. Modules: (1) dissolution-kinetics engine with 16 release models fitted by nonlinear least squares in the F(%) domain, AIC/AICc/MSC ranking and Akaike weights, Korsmeyer–Peppas F≤60% rule, Hopfenberg geometry exponents including the Karasulu half-sphere and triangle, results compared with DDSolver 1.0 outputs; (2) pseudo-ternary phase-diagram tool with polygon area and centroid calculation, in use since 2001; (3) f1/f2 similarity factors and model-independent profile metrics; (4) dose–response (LD50) and t-test utilities. Detailed bilingual guides with Crossref-verified references accompany the tools. Sites: https://ptcalc.net (English), https://ptcalc.tr (Turkish). Türkçe: Open-source computational tools for pharmaceutical technology: dissolution kinetics engine, pseudo-ternary phase diagram, f1/f2 similarity factors, dose–response analysis and t-test.