Fc gamma RIIa, IIIa and IIIb gene polymorphisms in Behcet's disease: do they have any clinical implications?
Articles > Article · 2008
Authors: Kenan AKSU, Gül KİTAPÇIOĞLU, Gökhan KESER, Afig BERDELİ, Gonca KARABULUT, S. KOBAK, M. OZMEN, VEDAT İNAL, Yasemin KABASAKAL, Fahrettin OKSEL, Hayriye KOÇANAOĞULLARI, E. DOGANAVSARGIL
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, Journal Indexed in SCI Expanded, International, 2008, vol 26
Summary
Objective. Behcets disease (BD) is a unique systemic vasculitis involving both arteries and veins of all sizes. Since Fc gamma receptors (Fc gamma R) are important in mediating various immune effector functions, Fc gamma R gene polymorphisms may affect the susceptibility to systemic inflammatory diseases such as BD. The aim of this study was to show the distribution of Fc gamma RIIa, IIIa ve IIIb receptor gene polymorphisms in BD, and to investigate possible genotype-phenotype relationships.