Fc gamma RIIa, IIIa and IIIb gene polymorphisms in Behcet's disease: do they have any clinical implications?
Makaleler > Tam Makale · 2008
Yazarlar: Kenan AKSU, Gül KİTAPÇIOĞLU, Gökhan KESER, Afig BERDELİ, Gonca KARABULUT, S. KOBAK, M. OZMEN, VEDAT İNAL, Yasemin KABASAKAL, Fahrettin OKSEL, Hayriye KOÇANAOĞULLARI, E. DOGANAVSARGIL
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2008, cilt 26
Özet
Objective. Behcets disease (BD) is a unique systemic vasculitis involving both arteries and veins of all sizes. Since Fc gamma receptors (Fc gamma R) are important in mediating various immune effector functions, Fc gamma R gene polymorphisms may affect the susceptibility to systemic inflammatory diseases such as BD. The aim of this study was to show the distribution of Fc gamma RIIa, IIIa ve IIIb receptor gene polymorphisms in BD, and to investigate possible genotype-phenotype relationships.