Electrochemical detection of anticancer drug Lumazine and DNA interaction by using carbon nanotube modified electrodes
Articles > Article · 2019
Authors: Hakan KARADENİZ, Kadriye Arzum ERDEM GÜRSAN
Journal of Research in Pharmacy, Journal Indexed in SCI Expanded, International, Scopus, 2019, vol 23, pp 682-688
Summary
The interaction of lumazine (LMZ) with dsDNA was investigated with differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS) by using disposable carbon nanotubes-modified pencil graphite electrode (CNTs-PGE).The passive adsorption process was used to modify the electrode surface by CNTs and then dsDNA was immobilized onto the modified PGEs.The performance of CNT-PGEs was studied by examining the optimum analytical conditions with DPV and then impedance method was performed to characterize the modification of CNTs onto the electrode surface.