Electrochemical detection of anticancer drug Lumazine and DNA interaction by using carbon nanotube modified electrodes

Makaleler > Tam Makale · 2019

Yazarlar: Hakan KARADENİZ, Kadriye Arzum ERDEM GÜRSAN

Journal of Research in Pharmacy, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Scopus, 2019, cilt 23, ss 682-688

DOI: 10.12991/jrp.2019.176

Özet

The interaction of lumazine (LMZ) with dsDNA was investigated with differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS) by using disposable carbon nanotubes-modified pencil graphite electrode (CNTs-PGE).The passive adsorption process was used to modify the electrode surface by CNTs and then dsDNA was immobilized onto the modified PGEs.The performance of CNT-PGEs was studied by examining the optimum analytical conditions with DPV and then impedance method was performed to characterize the modification of CNTs onto the electrode surface.

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