GC-MS Investigation and Acetylcholinesterase Inhibitory Activity of Galanthus rizehensis
Makaleler > Tam Makale · 2013
Yazarlar: Buket BOZKURT, Nehir SOMER, Gülen İrem KAYA, Mustafa Ali Onur, Jaume Bastida, Strahil Berkov
Zeitschrift für Naturforschung C, Uluslararası, Wos, 2013, cilt 68, ss 118-124
Özet
GC-MS (gas chromatography-mass spectrometry) analyses of alkaloids in the aerial parts and bulbs of Galanthus rizehensis Stern (Amaryllidaceae), collected during two different vegetation periods, was performed. Twenty three alkaloids were identified in four different alkaloid extracts. Acetylcholinesterase (AChE) inhibitory activities of the alkaloid extracts were tested. Both the highest alkaloid diversity and the most potent inhibitory activity (IC50 12.94 microg/ml) were obtained in extracts from the bulbs of G. rizehensis collected during the fruiting period.