Factors Associated With Persistent Increase in Level of Alanine Aminotransferase in Patients With Chronic Hepatitis B Receiving Oral Antiviral Therapy
Articles > Article ยท 2017
Authors: Ira M. JACOBSON, Mary K. Washington, Maria BUTI, Alexander THOMPSON, Nezam Afdhal, Robert FLISIAK, Ulus Salih AKARCA, Konstantin G. TCHERNEV, John F. FLAHERTY, Raul Aguilar SCHALL, Robert P. MYERS, G. Mani SUBRAMANIAN, John G. MCHUTCHISON, Zobair YOUNOSSI, Patrick MARCELLIN, Keyur Patel
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, Journal Indexed in SCI Expanded, International, 2017, vol 15, pp 1087-1094.e2
DOI: 10.1016/j.cgh.2017.01.032
Summary
BACKGROUND & AIMS: Despite complete suppression of viral DNA with antiviral agents, in some patients with chronic hepatitis B (CHB), serum levels of alanine aminotransferase (ALT) do not normalize. We investigated factors associated with persistent increases in ALT level in patients with CHB given long-term tenofovir disoproxil fumarate.