The expression of astroglial glutamate transporters in patients with focal cortical dysplasia: an immunohistochemical study
Makaleler > Tam Makale · 2009
Yazarlar: Mustafa Onur Ulu, Taner Tanriverdi, Buge Oz, Hüseyin BİÇEROĞLU, Cihan Isler, Berna Senel Eraslan, Cigdem Ozkara, Emin Ozyurt, Mustafa Uzan
ACTA NEUROCHIRURGICA, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2009, cilt 152, ss 845-853
DOI: 10.1007/s00701-009-0548-2
Özet
An abnormal increase in the extracellular glutamate is thought to play a crucial role in the initiation, spread, and maintenance of seizure activity.In normal conditions, the majority of this excess glutamate is cleared via glial glutamate transporters (EAAT-1 and EAAT-2). We aimed to examine the immunohistochemical expression of these transporters in the dysplastic tissues of patients with focal cortical dysplasia (FCD).