Hydrogel Formulations to Investigate Lung Cancer Mechanism
Articles > Article · 2025
Authors: Aysel Saskara, Yagmur Arslan, Özlem YEŞİL ÇELİKTAŞ
Thoracic Research and Practice, International, Scopus, 2025, vol 26, pp 10-11
DOI: 10.4274/thoracrespract.2025.s004
Summary
INTRODUCTION: . MATERIAL AND METHODS: . RESULTS: . CONCLUSION: Despite significant progress, variability in dECM composition and crosslinking chemistry still challenges reproducibility and bioactivity. Moreover, current hydrogel-based models often lack immune cell components and vascular complexity, limiting their ability to fully emulate the native TME. Future efforts should integrate dECM-based hydrogels with organoid and microfluidic systems, supported by multi-omics profiling, to achieve patient-specific and physiologically relevant lung cancer models.