Holistic approach to cell characteristics and behavioral analysis
Makaleler > Tam Makale · 2019
Yazarlar: Hüseyin AKTUĞ, Berrin ÖZDİL BAY, Duygu Çalik Kocatürk, Eda Açikgóza
Critical Reviews in Oncogenesis, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Scopus, 2019, cilt 24, ss 21-26
DOI: 10.1615/critrevoncog.2019029527
Özet
Cancer is a group of diseases of our era that affects not only medical status but also lowers the tone of social and emotional well-being. It also has severe impacts on economies. Cancer cells are linked to the somatic cells and stem cells, with their characteristic similarities and differences. Variations in cell-signaling pathways, such as cell death and proliferation balances, kinetic behavior of the cells, and their differentiation potentials, are the featured parameters for therapeutic targeting. The detection of target points should be based not only on the molecular biology methods but also on the physical and topological analyses from the aspect of “geography is fate.” In this review, we focus on the importance of the holistic analyses of intracellular and extracellular dynamics and multidisciplinary cooperation.