Comparing the Fatty Acid Composition and Neuroprotective Effects of Some Lamiaceae Taxa from Turkey
Makaleler > Tam Makale · 2022
Yazarlar: Tuğçe FAFAL, Gizem Kaftan, Pelin Taştan, Bijen KIVÇAK, Güliz ARMAGAN
Chemistry of Natural Compounds, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Scopus, 2022, cilt 58, ss 208-212
DOI: 10.1007/s10600-022-03642-9
Özet
<p>This study aims to analyze the fatty acid composition and neuroprotective potential of some selected Lamiaceae taxa from Turkey. For this purpose, methanol extracts of <em>Lamium album</em> L., <em>Lamium garganicum</em> L., <em>Phlomis rigida</em> Labill., <em>Salvia syriaca</em> L., <em>Salvia sclarea</em> L., and <em>Stachys cretica</em> subsp. <em>anatolica</em> Rech. f. were investigated for their activity against hydrogen peroxide induced neuronal cell death. The fatty acid compositions were analyzed by GC-FID, and the IA and IT indices and the ω3/ω6 ratio were also calculated. Saturated and unsaturated fatty acids of selected Lamiaceae species were measured to range from 8.92–17.59% and 75.13–84.57%, respectively. <em>Phlomis rigida</em> with the highest ω3/ω6 was shown to have the highest neuroprotection against H2O2-induced cell toxicity.</p>