Lecithin/chitosan nanoparticles of clobetasol-17-propionate capable of accumulation in pig skin
Makaleler > Tam Makale · 2009
Yazarlar: Taner ŞENYİĞİT, Fabio SONVİCO, Stefano BARBİERİ, Kevser Özgen ÖZER, Patrizia SANTİ, Paolo COLOMBO
Journal of Controlled Release, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2009, cilt 142, ss 368-373
DOI: 10.1016/j.jconrel.2009.11.013
Özet
In this study, clobetasol-17-propionate (CP) loaded lecithin/chitosan nanoparticles were studied with special attention to the transport of the active agent across the skin in vitro. Nanoparticles were characterized by measuring particle size, zeta potential, polydispersity index and encapsulation efficiency. The morphology of nanoparticles was evaluated by transmission electron microscopy.