Current view and outcome of ITI therapy - A change over time?
Articles > Article ยท 2016
Authors: K. HOLSTEIN, A. BATOROVA, M. CARVALHO, K. FIJNVANDRAAT, P. HOLME, Ramazan Kaan KAVAKLI, T. LAMBERT, A. ROCINO, V. JIMENEZ-YUSTE, J. Astermark
Thrombosis Research, Journal Indexed in SCI Expanded, International, WoS, 2016, vol 148, pp 38-44
DOI: 10.1016/j.thromres.2016.10.015
Summary
Introduction: Inhibitor development in people with haemophilia is a serious complication that may require intensive and costly interventions. The goal of inhibitor management should be permanent inhibitor eradication through immune tolerance induction (ITI), but well-designed studies are lacking and the management of patients is therefore defined by the experience and views of the clinician.