PER-1 production in a urinary isolate of Providencia rettgeri
Articles > Article · 2004
Authors: Gülden BAHAR, Bayrı ERAÇ, ALİ MERT, Z GULAY
JOURNAL OF CHEMOTHERAPY, Journal Indexed in SCI Expanded, International, 2004, vol 16, pp 343-346
DOI: 10.1179/joc.2004.16.4.343
Summary
A Providencia rettgeri strain resistant to extended-spectrum cephalosporins and intermediate to aztreonam was isolated from the urine of a patient hospitalized in the urology clinic of SSK Educational Hospital in Ankara. Clavulanic acid restored the activity of extended-spectrum cephalosporins, suggesting that the strain was harboring an extended-spectrum beta-lactamase. Since the PER-1 enzyme is widespread in Turkey, and had been already detected in a related species such as Proteus mirabilis, the Providencia strain was suspected of harboring a PER-1 enzyme, which was indeed detected by PCR. This is the first description in a P. rettgeri isolate of a PER-1 enzyme which is widespread among Acinetobacter baumanni and Pseudomonas aeruginosa strains in Turkey.