The prevalence of Sjogren's syndrome in adult women
Articles > Article · 2006
Authors: Yasemin KABASAKAL, Gül Kitapçıoğlu, T. Turk, Gonca KARABULUT, İsabel Raika DURUSOY, Emine Nihal METE GÖKMEN, S. Eğrilmez, Taner AKALIN
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY, Journal Indexed in SCI Expanded, International, 2006, vol 35, pp 379-383
DOI: 10.1080/03009740600759704
Summary
<p>Objectives: The aim of this study was to determine the prevalence of primary Sjogren's syndrome (pSS) according to European criteria (1993) and to the US-European Consensus Group (US-EU) criteria (2002) in adult women in Bornova, Izmir, Turkey.</p><p>Materials and method: The study was designed as a two-phase cross-sectional survey consisting of a baseline questionnaire and collection of blood samples and clinical examination. In the initial phase, positivity for autoantibodies Ro(SS-A), La(SS-B), rheumatoid factor (RF), and anti-nuclear antibodies (ANA) was determined, and in the clinical phase, clinical examination, salivary and ocular tests were performed. Minor salivary gland biopsy was performed for those who had at least three of these five criteria positive.</p><p>Results: In our sample the prevalence of SS was 1.56% [95% confidence interval (CI) 0.92-2.66] according to the European criteria and 0.72% (95% CI 0.33-1.57) according to the US-EU criteria.</p><p>Conclusion: To prevent the loss in diagnosis of pSS, the addition of ANA, RF, and tear break-up time (BUT) tests to US-EU criteria would be appropriate.</p>