Long-term Intense 18F-FDG Uptake by the Homeostatic Matrix-associated Inflammatory Response May Mimic Malignancy Recurrence

Articles > Article · 2023

Authors: Fatih TAMER, Bülent YAZICI, Aylin ORAL, Ayşegül AKGÜN

Molecular Imaging and Radionuclide Therapy, International, Scopus, 2023, vol 32, pp 233-236

DOI: 10.4274/mirt.galenos.2023.92499

Summary

A 70-year-old man underwent right upper lobectomy for lung adenocarcinoma.During the operation, hemostatic matrix (as known Floseal ® ) was used to prevent pulmonary laceration-associated bleeding.When 18 F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography was performed for staging after surgery, intense 18 F-FDG uptake was observed in the cicatricial fibrotic tissue in the operation area, and no significant change was observed in that area during the 4-year follow-up.Because it remained stable for several years without treatment, this finding was thought to be due to a foreign body reaction caused by the homeostatic material.

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