The clinical presentation and outcomes of COVID-19 in immunocompromised hosts in comparison to comorbid and immunocompetent patients: retrospective study of 384 cases
Makaleler > Tam Makale · 2024
Yazarlar: Ziya Karimov, Gunay Huseynova, Hakan Kiriş, Cansu Tongel, Aynur Aliyeva, Nur SOYER, Nigar Abdullayeva, Ömer Selim UNAT, Özen KAÇMAZ BAŞOĞLU, Abdullah SAYINER, Mehmet Sezai TAŞBAKAN
Ege Tıp Dergisi, Uluslararası, 2024, cilt 63, ss 192-198
DOI: 10.19161/etd.1256543
Özet
Objective: Immunocompromised hosts (ICH) are at a higher risk of severe infections and mortality. This study aimed to examine the clinical manifestations and outcomes of ICH who were admitted to the hospital for COVID-19. Method: A total of 384 patients (mean age 61.515.9 y, 168 female) who were hospitalized between March 2020 and December 2020 were included in the study. These patients were examined in three groups: the ICH (n=40), comorbid patients (n=101), and the control group comprising immunocompetent patients without any comorbidities (n=243). All clinical and laboratory data were retrieved from the electronic hospital records and compared between the three groups retrospectively. Results: The mean age was 61.215.0 for ICH, 66.112.3 for comorbid, and 59.617.0 for control groups (p=0.003). We found that the mean leukocyte and neutrophil counts, C-reactive protein (CRP), ferritin, and D-Dimer levels were significantly higher and the albumin level was lower in ICH compared to the other two groups (p