Aqueous-phase Suzuki–Miyaura cross-coupling reactions catalyzed by Pd-NHC complexes
Makaleler > Tam Makale · 2009
Yazarlar: Hayati TÜRKMEN, Rahime CAN, BEKİR ÇETİNKAYA
Dalton Transactions, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2009, ss 7039-7039
DOI: 10.1039/b907032j
Özet
Cleavage reactions of [PdBr(2)(NHC)](2) with two equiv. of pyridine derivatives (L), having one or two carboxylic acid groups [L = NC(5)H(4)-2-COOH, NC(5)H(4)-3-COOH, NC(5)H(4)-4-COOH, or NC(5)H(3)-2,6-(COOH)(2) in chloroform or DMSO, respectively, afforded the monomeric mixed ligand complexes trans-[PdBr(2)(NHC)L] (1-4) which, due to deprotonation of the carboxylic acid functionality, are water soluble in KOH. The catalytic activity of complexes 1-4 in aqueous Suzuki-Miyaura cross-coupling reactions were evaluated and compared. The dicarboxylic functionality enhances the catalyst reactivity and stability and the carboxylate derived from 4 could be easily recovered and reused for several cycles under the mild reaction conditions.