Diverse effects of calcium channel blockers in the collar model
Makaleler > Tam Makale · 2005
Yazarlar: Zeliha KERRY, MUKADDER YASA, Gülnur SEVİN, Buket REEL, Günay YETİK ANACAK, A OZER
ACTA CARDIOLOGICA, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2005, cilt 60, ss 493-499
Özet
Objective - Calcium channel blockers (CCBs) are among the most frequently prescribed cardiovascular drugs. It has been shown that these drugs have antiatherosclerotic effects in both experimental and clinical settings. However, calcium channel blockers have markedly different chemical structures and different effects on the cardiovascular system.We investigated the effect of CD-832, a Ca+2 channel antagonist, on collar-induced intimal thickening, as well as accompanied reactivity changes in rabbit carotid artery.