Computational approaches for antibody-based drug design
Book chapter > Chapter Other Book ยท 2024
Authors: Sude Gunes, Ipek Arkca, Seref Berk Atik, Fulden Ulucan-Karnak, Humeyra Taskent Sezgin, Arzu Uyar
Advances in Drug Delivery Systems for Healthcare, Chapter Other Book, International, 2024, pp 11-1, ,
DOI: 10.1088/978-0-7503-5613-8ch11
Summary
This chapter focuses on the structure-function-dynamics of antibodies and their importance in the pharmaceutical sector and summarizes how recent computational tools play a vital role in the development and production of antibody and antibody-based therapeutics. We present here general protocols for how to use current computational tools efficiently. In the last part of this chapter, we focus on the great market value of these antibody-based targeted therapies, growing investment of pharmaceutical industry into mAb therapies as the personalized medicine field is expanding.