Computational approaches for antibody-based drug design
Kitapta bölümler > Diğer · 2024
Yazarlar: Sude Gunes, Ipek Arkca, Seref Berk Atik, Fulden Ulucan-Karnak, Humeyra Taskent Sezgin, Arzu Uyar
Advances in Drug Delivery Systems for Healthcare, Diğer, Uluslararası, 2024, ss 11-1, ,
DOI: 10.1088/978-0-7503-5613-8ch11
Özet
This chapter focuses on the structure-function-dynamics of antibodies and their importance in the pharmaceutical sector and summarizes how recent computational tools play a vital role in the development and production of antibody and antibody-based therapeutics. We present here general protocols for how to use current computational tools efficiently. In the last part of this chapter, we focus on the great market value of these antibody-based targeted therapies, growing investment of pharmaceutical industry into mAb therapies as the personalized medicine field is expanding.