Caffeic acid phenethyl ester triggers apoptosis through induction of loss of mitochondrial membrane potential in CCRF-CEM cells
Makaleler > Tam Makale · 2010
Yazarlar: Çığır BİRAY AVCI, Cumhur GÜNDÜZ, Yusuf Baran, Fahri ŞAHİN, Sunde YILMAZ SÜSLÜER, Zeynep Ozlem DOĞAN, Güray SAYDAM
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2010, cilt 137, ss 41-47
DOI: 10.1007/s00432-010-0857-0
Özet
CAPE (caffeic acid phenethyl ester) is one of the most valuable and investigated component of propolis which is composed by honeybees. In the current study, we aimed at examining apoptotic effects of CAPE on CCRF-CEM leukemic cells and at determining the roles of mitochondrial membrane potential (MMP) in cell death.