The fate and function of non-coding RNAs during necroptosis
Makaleler > Tam Makale · 2024
Yazarlar: Esra Bozgeyik, Alperen Elek, Zekihan Gocer, Ibrahim Bozgeyik
Epigenomics, Uluslararası, Wos, 2024, cilt 16, ss 901-915
DOI: 10.1080/17501911.2024.2354653
Özet
Necroptosis is a novel form of cell death which is activated when apoptotic cell death signals are disrupted. Accumulating body of observations suggests that noncoding RNAs, which are the lately discovered mystery of the human genome, are significantly associated with necroptotic signaling circuitry. The fate and function of miRNAs have been well documented in human disease, especially cancer. Recently, lncRNAs have gained much attention due to their diverse regulatory functions. Although available studies are currently based on bioinformatic analysis, predicted interactions desires further attention, as these hold significant promise and should not be overlooked. In the light of these, here we comprehensively review and discuss noncoding RNA molecules that play significant roles during execution of necroptotic cell death.