Elevated risk of motor vehicle accidents in patients with obstructive sleep apnea syndrome: A case-control study
Bildiriler > Özet Bildiri
Yazarlar: Özen KAÇMAZ BAŞOĞLU, Mehmet Sezai TAŞBAKAN
European Respiratory Journal, , , Uluslararası, Özet Bildiri, Wos, cilt 42, ss P4016-P4016
DOI: 10.1183/13993003/erj.42.suppl_57.p4016
Özet
Background : The risk of motor vehicle accidents (MVAs) is increased in obstructive sleep apnea syndrome (OSAS) patients. The present case-control study aimed to determine accident rate in OSAS patients, and to identify disease-related factors associated with accident risk. Methods: Demographic, anthropometric, clinical and polysomnograhic parameters of 312 OSAS patients were compared to 156 age- and sex-matched primary snoring subjects. Results: Rate of OSAS patients reporting accident was higher than snoring subjects (21.2% vs. 11.5%, p=0.011), and OSAS was associated with a 2.06 (95% CI, 1.17 to 3.61, p=0.012) increase in accident rate. OSAS patients with older age (p=0.001), male gender (p=0.001), increased neck circumference (p=0.002), Epworth sleepiness score (ESS) (p<0.0001) and apnea-hypopnea index (AHI) (p=0.039) had more MVAs than patients without accident. Daytime sleepiness was associated with a 2.74-fold increase (95% CI, 1.54 to 4.87, p=0.001) in accident rate. Age (r=-0.163, p=0.004), neck circumference (r=0.175, p=0.002), ESS (r=0.297, p<0.0001) and AHI (r=0.135, p=0.017) were correlated significantly with MVA risk. In multivariate linear regression analysis, accident risk was associated with neck circumference and ESS (p<0.0001). Besides, accident risk could be excluded in OSAS patients with neck circumference<43cm and ESS<11 (sensitivity 33.3%, specificity 85.8%). Conclusions: The present results support that OSAS patients have a twofold higher risk of traffic accidents than control subjects, and increased neck circumference and excessive daytime sleepiness are useful in predicting OSAS patients at higher risk of having accidents.