Quercetin inhibits swarming motility and activates biofilm production of Proteus mirabilis possibly by interacting with central regulators, metabolic status or active pump proteins
Articles > Article · 2018
Authors: Abdurrahman Aygül, Ismail Ozturk, Fatma Feriha ÇİLLİ, Şafak ERMERTCAN
Phytomedicine, Journal Indexed in SCI Expanded, International, WoS, 2018, vol 57, pp 65-71
DOI: 10.1016/j.phymed.2018.12.014
Summary
Background: Via its virulence factors such as swarm differentiation, biofilm and hemolysin production, urease enzyme, Proteus mirabilis causes urinary tract infections (UTIs), especially in complicated cases. Anti-pathogenic compounds attenuate the virulence of bacteria without showing 'cidal' activity and carry the potential to be used in the prevention and treatment of infectious diseases.