P3468What we learned from the analysis of first 301 patients from the Turkish Peripartum Cardiomyopathy Registry?
Makaleler > Tam Makale · 2018
Yazarlar: M Kayikcioglu, L Tokgozoglu, M Biteker, M A Akil, F Ertas, Sanem NALBANTGİL, E Yilmaz, D C Yilmaz, L Askin, L D Asarcikli, F O Mutluer, D Ural, A Temizhan, ARTEMIS 1 Investigators
European Heart Journal, Uluslararası, Wos, 2018, cilt 39
DOI: 10.1093/eurheartj/ehy563.p3468
Özet
Background: Peripartum cardiomyopathy (PPCM) is the major cause of acute heart failure in the peripartum period. ARTEMIS-1 is a retrospective registry conducted with the aim of providing insight to the real-world management of PPCM in Turkey. Methods: 301 patients with the diagnosis of PPCM during the last 5 years, were retrospectively enrolled from 44 centers. Participating centers provided patient information including presentation, co-morbidities, diagnosis, family history, treatment patterns, relevant laboratory values, and in-hospital and 1 year outcomes via a standard questionnaire. Results: The mean age was 30±7 years. 6.8% were diabetic and 12.3% patients had a hypertensive disorder. Presenting symptom was dyspnea in 94%. In 73% the symptoms were initiated in postpartum period. Drug therapy initiated included mineralocorticoid receptor antagonists (52%), beta-blockers (98%) and inotropics (16%). Bromocriptine was only used in 6.4%. In-hospital mortality was 6.84%. Neonatal death rate was 4.6%. Long-term follow-up was available in 81% for 1 year. 3 patients were died during follow-up and complete recovery was afforded in 35%. Recovery was associated with left ventricular (LV) ejection fraction (EF), LV end-diastolic size, right ventricular EF, systolic pulmonary arterial pressure, age at diagnosis, CRP and haemoglobin levels, and systolic blood pressure.