Basic Fibroblast Growth Factor Retains Its Biological Activity In Vitro When Delivered Through Degradation of Gelatin Microspheres
Articles > Article · 2011
Authors: Aylin ŞENDEMİR, Russell D. Jamison
\n Yıl: 2011 Sayı: 3\n 65-70\n \n, International, 2011, vol 5, pp 65-70
Summary
In designing delivery systems for growth factors and other protein drugs, it is important to know what percentage of the loaded protein will be delivered in biologically active form. This work evaluates the release system of basic fibroblast growth factor (bFGF) through gelatin microspheres. The results indicate that there is no detectable loss of mitogenic activity of the growth factor on fibroblastic cells after delivery