Polypharmacy, Physical and Nutritional Status, and Depression in the Elderly: Do Polypharmacy Deserve Some Credits in These Problems?
Makaleler > Tam Makale · 2020
Yazarlar: Sibel EYİGÖR, Yesim Gokce Kutsal, Fusun Toraman, Bekir Durmus, Kutay Ordu Gokkaya, ALİ AYDENİZ, Nurdan Paker, Pinar Borman
Experimental Aging Research, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2020, cilt 47, ss 79-91
DOI: 10.1080/0361073x.2020.1846949
Özet
Background: To investigate the association of polypharmacy with physical function, nutritional status, and depression in the elderly.Method: The study included 675 people aged over 65 years from 8 centers in various geographical regions. The polypharmacy status was categorized as non-polypharmacy (0–4 drugs), polypharmacy (≥5 drugs). The subjects’ physical function was assessed based on their “physical activity levels, Holden ambulation scores, gait speeds, and hand grip strengths”; their nutritional status based on the “Mini Nutritional Assessment (MNA)”; and their psychological status based on the “Center for Epidemiologic Studies Depression Scale -CES-D”.Results: The presence of polypharmacy in this population was found to be 30% (n = 203). A statistically significant difference was found between the groups on the level of physical activity, Holden ambulation score, and nutrition status (p < .05). There was a statistically significant difference between the groups also on hand grip strength, MNA score, Charlson score (p < .05).Conclusion: Polypharmacy was observed to have a significant association with physical function, nutrition, and depression in the elderly aged ≥ 65 years.