Epicardial fat, body mass index, and triglyceride are independent contributors of serum fibroblast growth factor 21 level in obese premenopausal women
Articles > Article · 2014
Authors: Z. I. Akyildiz, SEVGİ POLAT, Banu Pınar ŞARER YÜREKLİ, G. U. Kocabas, KAMİL TÜLÜCE, S. Y. Tuluce, UĞUR KOCABAS, GİRAY BOZKAYA, ARİF YÜKSEL, CEM NAZLI
Journal of Endocrinological Investigation, Journal Indexed in SCI Expanded, International, WoS, 2014, vol 38, pp 361-366
DOI: 10.1007/s40618-014-0185-3
Summary
Purpose The hormone fibroblast growth factor 21 (FGF-21) regulates carbohydrate and lipid homeostasis. FGF-21 represents an attractive novel therapy for obesity since administration of FGF-21 has been shown to improve metabolic abnormalities in obese animal models. We investigated FGF-21 and its relationship with epicardial fat thickness (EFT), metabolic parameters, and inflammatory markers in premenopausal obese women compared to controls with similar Systematic Coronary Risk Evaluation (SCORE) project risk profiles.