Gene polymorphisms of matrix metalloproteinase-2,-9 and-12 in periodontal health and severe chronic periodontitis
Articles > Article · 2008
Authors: Ali GÜRKAN, Gülnur EMİNGİL, Buket Han SAYGAN, FATMA GÜL ATİLLA, SERHAT ÇINARCIK, Timur KOESE, Afig BERDELİ
ARCHIVES OF ORAL BIOLOGY, Journal Indexed in SCI Expanded, International, 2008, vol 53, pp 337-345
DOI: 10.1016/j.archoralbio.2007.11.002
Summary
Aim: Matrix metalloproteinases (MMPs) are involved in periodontal tissue remodeling and degradation. MMP polymorphisms could alter transcription and function of these enzymes. The aim of this study was to investigate MMP-2, MMP-9 and MMP-12 gene polymorphisms in relation to susceptibility to severe chronic periodontitis (CP).