Antiprotozoal alkaloids from Galanthus trojanus
Articles > Article · 2011
Authors: Gülen İrem KAYA, Buket Sarikaya, Mustafa Ali Onur, Nehir SOMER, Francesc VILADOMAT, Carles CODINA, Jaume BASTIDA, Ina L. Lauinger, Marcel Kaiser, Deniz Tasdemir
PHYTOCHEMISTRY LETTERS, Journal Indexed in SCI Expanded, International, 2011, vol 4, pp 301-305
DOI: 10.1016/j.phytol.2011.05.008
Summary
Two new alkaloid N-oxides, 1-O-acetyldihydromethylpseudolycorine N-oxide, and 11-hydroxyvittatine N-oxide, ten known alkaloids; arolycoricidine, haemanthamine, O-methylnorbelladine, narcidine, dihydrolycorine, 8-O-demethylmaritidine, stylopine and protopine, nicotinic acid and tyramine were isolated from Galanthus trojanus A. P. Davis & N. Ozhatay (Amaryllidaceae). The chemical structures of the isolates were elucidated by UV, IR, MS, CD, 1D and 2D NMR experiments. The in vitro antiprotozoal and cytotoxic potentials of the compounds were also evaluated. (C) 2011 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.