Coexistence of Takayasu's arteritis with familial Mediterranean fever
Articles > Article · 2011
Authors: Figen YARGUCU ZİHNİ, Melike KALFA, Panar Talu Ocakci, Figen TARHAN, Mustafa PARILDAR, Gökhan KESER, Kenan AKSU
RHEUMATOLOGY INTERNATIONAL, Journal Indexed in SCI Expanded, International, 2011, vol 32, pp 1675-1678
DOI: 10.1007/s00296-011-1853-7
Summary
Familial Mediterranean fever (FMF) is the most common autoinflammatory disease characterized by recurrent self-limited attacks of fever, accompanied with peritonitis, pleuritis or arthritis. It is well known that FMF may coexist with vasculitic pathologies, especially with those involving small and medium vessels. Among the vasculitic pathologies reported to be associated with FMF, Henoch-Schonlein purpura and polyarteritis nodosa come the first, possibly followed up by protracted febrile myalgia. However, coexistence of FMF with any large vessel vasculitis has not been reported to date. Here, we present a case with FMF who later developed Takayasu arteritis, with a severe disease course, being resistant to corticosteroids and conventional immunosuppressive agents, and requiring infliximab treatment.