Characterization of poly(vinylferrocenium) coated surfaces and their applications in DNA sensor technology
Makaleler > Tam Makale · 2010
Yazarlar: Filiz Kuralay, Kadriye Arzum ERDEM GÜRSAN, Serdar Abaci, Haluk Ozyoruk, Attila Yildiz
Journal of Applied Electrochemistry, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Wos, 2010, cilt 40, ss 2039-2050
DOI: 10.1007/s10800-010-0185-8
Özet
Poly(vinylferrocenium) (PVF+) modified gold (Au) electrode was developed in this study for the electrochemical sensing of deoxyribonucleic acid (DNA) hybridization based on the oxidation signals of polymer and guanine, and also for the electrochemical investigation of interaction of anticancer drug, mitomycin C (MC) and DNA immobilized onto PVF+ modified Au electrode. PVF+ modified Au electrode was prepared by electrooxidation of poly(vinylferrocene) PVF at +0.7 V versus Ag/AgCl reference electrode. The polymer modified electrode and DNA immobilized polymer modified electrode were characterized by X-ray photoelectron (XPS), Fourier transform infrared-attenuated total reflentance (FTIR-ATR) and alternating current (AC) impedance spectroscopy. For application studies, differential pulse voltammetry (DPV) technique was used.