Understanding and management of anti-N-methyl-D-aspartate receptor encephalitis from a child psychiatry perspective: report of five cases
Articles > Article · 2022
Authors: Nurhak DOĞAN, Hilal Subasi, Zeynep İrem ERBASAN, Akin Tahillioglu, Seda KANMAZ, Sezen KÖSE, Nazlı Burcu ÖZBARAN, Hepsen Mine SERİN
Neurocase, International, WoS, 2022, vol 28, pp 239-245
DOI: 10.1080/13554794.2022.2086468
Summary
Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a rare autoimmune entity in psychiatry literature that occurs when antibodies attack NMDA-type glutamate receptors in the brain. Principle clinical features include a neurological domain such as seizure, orofacial dyskinesia, dystonia, and choreic-like movements of extremities. Also the psychiatric manifestations of this form of encephalitis may vary from psychotic-like symptoms to mood symptoms like depression or mania. Herein we report on five female child cases diagnosed with anti-NMDAR encephalitis, presented with both neurological and psychiatric clinical picture, and highlight the trajectory of disorder from a psychiatric perspective.