Understanding and management of anti-N-methyl-D-aspartate receptor encephalitis from a child psychiatry perspective: report of five cases

Makaleler > Tam Makale · 2022

Yazarlar: Nurhak DOĞAN, Hilal Subasi, Zeynep İrem ERBASAN, Akin Tahillioglu, Seda KANMAZ, Sezen KÖSE, Nazlı Burcu ÖZBARAN, Hepsen Mine SERİN

Neurocase, Uluslararası, Wos, 2022, cilt 28, ss 239-245

DOI: 10.1080/13554794.2022.2086468

Özet

Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a rare autoimmune entity in psychiatry literature that occurs when antibodies attack NMDA-type glutamate receptors in the brain. Principle clinical features include a neurological domain such as seizure, orofacial dyskinesia, dystonia, and choreic-like movements of extremities. Also the psychiatric manifestations of this form of encephalitis may vary from psychotic-like symptoms to mood symptoms like depression or mania. Herein we report on five female child cases diagnosed with anti-NMDAR encephalitis, presented with both neurological and psychiatric clinical picture, and highlight the trajectory of disorder from a psychiatric perspective.

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