Validation Study of Rome Criteria for Assessing COPD Exacerbation Severity and Predicting Clinical Outcomes:TTS-COPD Assembly
Bildiriler > Özet Bildiri
Yazarlar: Ayşe Baha, CANER BAYSAN, Sibel Atis Nayci, Eylem Sercan Ozgur, Tugce Karamustafaoglu, Elif Sen, Elif Selcuk, Gözde Mit, Aylin Ozgen Alpaydin, Burcu Ozturk, Kubra Taskaraca Karabacak, Nurdan Kokturk, Sule Akbulut, Oya Baydar, Yelda Varol, Sumeyye Kodalak, Dorina Esendagli, Alev GÜRGÜN, Elnaz Emdadian, Zehra Nur TÖREYİN, Asli Alkan, Umran Sertcelik, Ipek Ozmen, Esra Ulu Elabed, Hatice Kilic, Mehmet Polatli, Osman Hilmioglu
Monitoring airway disease, , , Uluslararası, Özet Bildiri, ss PA3627-PA3627
DOI: 10.1183/13993003.congress-2025.pa3627
Özet
Validation Study of Rome Criteria for Assessing COPD Exacerbation Severity and Predicting Clinical Outcomes:TTS-COPD Assembly Objective: The Rome classification was introduced to assess the severity of acute exacerbation(AE) of COPD using easily measurable variables. However, its global validation remains unclear. This study aims to evaluate the validity of the Rome criteria in determining COPD-AE severity and prognosis in Turkiye. Methods: This multicenter study included 750 COPD-AE patients to emergency departments and outpatient clinics. Based on Rome criteria, patients were classified into 3 groups:mild, moderate, severe COPD-AE. Results:13.2% were in the mild,63.9% in the moderate, and 22.9% in severe group. In demographic and clinical characteristics, age (p=0.001), Charlson index (p=0.007), and smoking status(p<0.001) differed significantly. Additionally, emergency visits, hospitalizations, and ICU admissions were more frequent in moderate and severe groups(p<0.001). Most mild cases were discharged (p<0.001), while most moderate and severe-AE cases required hospitalization (p<0.001). The severe-AE had significantly higher risk of ICU admission(p<0.001), NIV (p<0.001), IMV(p<0.001), in-hospital mortality(p<0.001), and 30-day mortality(p=0.015). Logistic regression analysis identified factors affecting AE severity:number of emergency visits(p=0.004,OR=0.70), number of ICU admission(p=0.001,OR=1.33), FEV1 (p<0.001,OR=1.00), USOT (p=0.019,OR=1.13), CPAP/BPAP(p=0.004,OR=1.39). Conclusion: The Rome criteria effectively assess exacerbation severity in COPD patients in secondary and tertiary care hospitals in Turkiye. This study supports their use in clinical practice to predict outcomes.