Preparation of Ca-alginate biopolymer beads and investigation of their decorporation characteristics for Sr-85, U-238 and Th-234 by in vitro experiments
Makaleler > Tam Makale · 2012
Yazarlar: Cem Gok, Udo Gerstmann, Vera Hoellriegl, Şule AYTAŞ
RADIATION PROTECTION DOSIMETRY, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2012, cilt 153, ss 47-55
DOI: 10.1093/rpd/ncs088
Özet
The aim of this work was to investigate whether Ca-alginate biopolymer beads (CaABBs) can be used to reduce the bioavailability of radionuclides in the gastrointestinal tract of humans. The uptake of strontium, uranium and thorium from a simulated gastrointestinal system was studied by in vitro techniques using CaABBs. This agent was prepared from Na-alginate through cross-linking with divalent calcium ions according to the egg-box model. The effects of process variables such as pH of the gastrointestinal juice, incubation time and solid-to-solution ratio for the removal of radionuclides from the gastrointestinal juice were investigated. The results suggest that CaABBs are a potent material for reducing the bioavailability of radionuclides with a high uptake efficiency in the gastrointestinal tract.