Ergothioneine produces relaxation in isolated rat aorta by inactivating superoxide anion.
Articles > Article · 2014
Authors: Göksel GÖKÇE, Mehmet Zuhuri ARUN
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, Journal Indexed in SCI Expanded, International, 2014, vol 18, pp 3339-45
Summary
OBJECTIVE: Ergothioneine (EGT) is a ubiquitous, sulphur-containing derivative of amino acid histidine, acquired by higher order plants and animals solely through dietary means. The antioxidant and cytoprotective effects of ergothioneine have been demonstrated by in vitro studies, but its physiological role remains unclear. This study aims to investigate the effects of ergothioneine (EGT) on basal and acetylcholine-stimulated activity of nitric oxide.