Brain Abscesses in Children: Results of 24 Children From a Reference Center in Central Anatolia, Turkey
Makaleler > Tam Makale · 2014
Yazarlar: MEHMET CANPOLAT, Ozgur Ceylan, HÜSEYİN PER, Gonca KOÇ, ABDULFETTAH TÜMTÜRK, Sefer Kumandas, TÜRKAN PATIROĞLU, Selim Doganay, HAKAN GÜMÜŞ, EKREM ÜNAL, Mehmet Kose, Sureyya Burcu Gorkem, Ali Kurtsoy, Mustafa Kursat Ozturk
JOURNAL OF CHILD NEUROLOGY, SCI Expanded İndekslerine Giren Dergi, Uluslararası, 2014, cilt 30, ss 458-467
Özet
Childhood brain abscesses are a rare and potentially life-threatening condition requiring urgent diagnosis and treatment. This retrospective study analyzed the clinical and radiologic findings of 24 (7 girl, 17 boys) cases with brain abscess. Mean age was 92.98 +/- 68.04 months. The most common presenting symptoms were nausea-vomiting (45.8%) and headache (41.7%). Brain abscess was most commonly located in the frontal region. Diffusion restriction was determined in 78.4% of lesions. The mean apparent diffusion coefficient value in these lesions was 0.511 +/- 0.23 x 10(-3) mm(2)/s. Cultures were sterile in 40% of cases. Antimicrobial therapy was given to only 16.7% of cases. Predisposing factors were identified in 91.6% of cases (congenital heart disease in 20.8% and immunosuppression in 20.8%). Mortality level was 12.5%. In conclusion, immunocompromised states, and congenital heart disease have become an important predisposing factor for brain abscesses. Effective and prompt management should ensure better outcome in childhood.