Brain regions associated with risk and resistance for bipolar I disorder: a voxel-based MRI study of patients with bipolar disorder and their healthy siblings
Articles > Article · 2014
Authors: Mehmet Çağdaş EKER, Fatma ŞİMŞEK, Evrim Ebru YILMAZER, Ömer KİTİŞ, Cem ÇINAR, Ozlem Donat Eker, Kerry Coburn, Ali Saffet GÖNÜL
BIPOLAR DISORDERS, Journal Indexed in SCI Expanded, International, 2014, vol 16, pp 249-261
DOI: 10.1111/bdi.12181
Summary
ObjectiveBipolar I disorder is a highly heritable disorder but not all siblings manifest with the illness, even though they may share similar genetic and environmental risk factors. Thus, sibling studies may help to identify brain structural endophenotypes associated with risk and resistance for the disorder.