Effects of salbutamol given by metered-dose inhaler on dispersion of ventricular repolarization
Articles > Article · 2011
Authors: Tugcin Bora POLAT, Eylem Ulaş SAZ, Mustafa Attila Nursoy
ANADOLU KARDIYOLOJI DERGISI-THE ANATOLIAN JOURNAL OF CARDIOLOGY, Journal Indexed in SCI Expanded, International, WoS, 2011, vol 11, pp 232-236
DOI: 10.5152/akd.2011.063
Summary
Objective: Salbutamol has previously been shown to increase the UT dispersion (aid), which may be associated with high risk of cardiac arrhythmia in asthmatics. Cardiac effects of salbutamol occur in dose-related manner and salbutamol dose given by metered-dose inhaler (MDI) during acute asthma attack is commonly lower than the dose given by nebulizer. This prospective cohort study aimed to assess the effect of salbutamol given by MDI on QTd in the course of moderate acute asthma attack.