Alterations of Serum Parathormone, Calcium, and Vitamin D Levels in End-Stage Heart Failure Cases Performed with Left Ventricular Assist Device Implantation
Makaleler > Tam Makale · 2018
Yazarlar: Pelin ÖZTÜRK, Yeşim KİRAZLI
Türk Osteoporoz Dergisi, SCI Expanded İndekslerine Giren Dergi, Uluslararası, Scopus, 2018, ss 5-10
DOI: 10.4274/tod.32659
Özet
Objective: Determination of the osteoporosis susceptibility in end-stage heart failure (ESHF) cases who underwent left ventricular assist device (LVAD) implantation by examining the alterations of serum parathormone (PTH), calcium, and vitamin D levels.Materials and Methods: Records of 375 patients who underwent continuous-flow LVAD implantation with diagnosis of ESHF in our clinic were retrospectively scanned.Thirty three patients with a minimum three months of follow-up, who had complete data about serum PTH, calcium, 25-hydroxyvitamin-D (25-OH-D), and pro-brain natriuretic peptide (pro-BNP) levels for pre and postoperative periods, as well as those with a bone mineral density (BMD) measurement were included in the study.In cases whose bone mineral density measurements made for lomber and hip region, for parameters that were worked with demographic data, initial and last follow-up serum values were recorded and statistical changes were examined.Furthermore, the effects of implanted LVAD type on the studied parameters were evaluated comparatively.Results: Totally 33 cases, four of female (12.1%), mean age and body mass index were found 52.7±12.0 years and 27.3±4.3kg/m 2 .Postoperative BMD examinations revealed that 50% of cases osteoporosis and 35.7% of osteopenia.Preoperative serum PTH, calcium, 25-OH-D, osteocalcin, urea, creatinine, glomerular filtration rate, and pro-BNP concentrations were 100.9±39.5 pg/mL, 8.9±0.8 mg/dL, Sol Ventrikül Destek Cihazı İmplantasyonu Uygulanan Son Dönem Kalp Yetmezlikli Olgularda Serum Parathormon, Kalsiyum ve Vitamin D Seviyelerindeki Değişim Alterations of Serum Parathormone, Calcium, and Vitamin D Levels in End-Stage Heart Failure Cases Performed with Left Ventricular Assist Device Implantation